The citizens of Genopole and the Paris-Saclay campus now have access to an essential technology for biotech. The mass spectrometry platform, accredited by Genopole and operated by LAMBE, has a new high-resolution mass spectrometer, an exceptionally capable device rarely seen in France. The €1.3 million in funding necessary for it was provided jointly by Genopole and the University of Évry-Paris Saclay. Ten years earlier, Genopole had financed the acquisition of an OrbiTRAP mass spectrometer (Thermo Fisher). This latter is now coupled to the DESIRS beamline at the Synchrotron Soleil facility, with whom LAMBE has been working for many years now.
The new device acquired in 2023, specifically a SELECT SERIES Cyclic IMS (Waters), is up and running at LAMBE, whose teams provide expertise in analytical chemistry, structural biology and biophysics. Because it is one of only three available in France, it is not surprising that its arrival at the mass spectrometry platform garnered great attention from the media.
This state of the art system offers unequalled performance for separation, characterization and quantification of molecular species in complex samples thanks to a combination of high resolution and cyclic ion mobility. The high‑resolution capacity enables the separation of a greater number of molecular species and eases structural determination.
Particularly versatile, this new mass spectrometer aims to meet the R&D demands of academic laboratories and companies within the Genopole ecosystem, as well as the University of Paris-Saclay.
The system provides compound mass measurement to a precision of <0.5 ppm, which permits the determination of the empirical formulae of small molecules with greater confidence.
This new technology is already serving the needs of five biocluster labs: SABNP, LBEPS1 Genomics Metabolics, GenHotel and LAMBE.
1 LBEPS: Laboratory of Exercise Biology for Performance and Health (University of Évry/IRBA)
